CMTX
CMTX is CMT caused by variants in genes on the X chromosome, usually GJB1. Women can be affected too, sometimes as severely as men. More in the glossary
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Genetic Cause of CMT2 Discovered?
A 2020 study linked JAG1 mutations to axonal CMT2 in two families. Updated in 2026: JAG1-related CMT now has its own OMIM entry, CMT2HH.
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The State of Research for Cures (2019)
The US-based CMTA (Charcot Marie Tooth Association) has a 12-year-old program called the Strategy to Accelerate Research (STAR) that is actively pursuing the causes and possible cures for CMT. STAR will cover nearly all CMT Type 1s and 2s, including types with as yet unidentified genetic causes.